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Intermittent Theta-burst (iTBS)

Intermittent Theta-burst or iTBS is a short 3 minute high frequency excitatory protocol that was recently approved by the FDA. They are patterned 5Hz bursts with each burst containing 3 pulses at 50Hz.

Train 1
10 bursts at 5.0Hz

10.0s
Train 2
10 bursts at 5.0Hz

10.0s
Train 3
10 bursts at 5.0Hz

10.0s
Train 4
10 bursts at 5.0Hz

10.0s
Train 5
10 bursts at 5.0Hz

10.0s
Train 6
10 bursts at 5.0Hz

10.0s
Train 7
10 bursts at 5.0Hz

10.0s
Train 8
10 bursts at 5.0Hz

10.0s
Train 9
10 bursts at 5.0Hz

10.0s
Train 10
10 bursts at 5.0Hz

10.0s
Train 11
10 bursts at 5.0Hz

10.0s
Train 12
10 bursts at 5.0Hz

10.0s
Train 13
10 bursts at 5.0Hz

10.0s
Train 14
10 bursts at 5.0Hz

10.0s
Train 15
10 bursts at 5.0Hz

10.0s
Train 16
10 bursts at 5.0Hz

10.0s
Train 17
10 bursts at 5.0Hz

10.0s
Train 18
10 bursts at 5.0Hz

10.0s
Train 19
10 bursts at 5.0Hz

10.0s
Train 20
10 bursts at 5.0Hz

10.0s
MT: 80% (10 bursts (3 pulses) at 5.0Hz) x (20 Trains) = 600 Pulses Total time: 00:03:47

Performed at 80% motor threshold. The train(s) consist of 30 pulses: 10 bursts (3 pulses/burst) delivered at 5.0 bursts per second for a total of 2 seconds followed by a break of 10.0 seconds and then repeated 20 times.

Inside each burst are 3 pulses delivered at 50 times per second or one pulse every 0.02 seconds.


Parameters

Stimulation typeBurst
Stimulus amplitude (% of MT)80
Burst frequency in train (Hz)5.0
Pulses frequency in burst (Hz)50
Bursts in train10
Number of trains20
Intertrain interval(s)10.0
Total time00:03:47
Total pulses600

Literature

Intermittent Theta-burst or iTBS is a short 3 minute high frequency excitatory protocol that was recently approved by the FDA. They are patterned 5Hz bursts with each burst containing 3 pulses at 50Hz.


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